LI-COR Introduces Three IRDye(R) Near-Infrared Fluorescence Resonance Energy Transfer (NIR-FRET) Protease Substrates
Gadgets, Site Feeds, aving.net November 13th, 2008
sensitive method to detect protease activity, measure potency of inhibitors
and screen compound collections for discovery of drug candidates. LI-COR
Biosciences now offers three different IRDye NIR-FRET Protease Substrates:
IRDye 800CW/QC-1 HIV-1, IRDye 800CW/QC-1 BACE, and IRDye 800CW/QC-1 CSP-3.
“These substrates have low intrinsic fluorescence due to self-quenching of
the conjugated dye by our novel IRDye QC-1 quencher,” says
strategic marketing manager. “These new substrates can be used for the highly
sensitive detection of protease activity via near-infrared fluorescence
detection on the Odyssey(R) Infrared Imaging System, Aerius(R) Automated
Imaging System, or other imaging systems with near infrared detection
capabilities.”
“NIR detection dramatical…
